PRP or Platelet Rich Plasma Therapy is the third type of Regenerative Injection Therapy (RIT). It is one of the most broadly utilized therapies by top athletes and other sportsmen. Numerous universities, institutions and medical centers around the world have conducted research and studies about PRP.
Platelet Rich Plasma is autologous which means it is extracted from the patient’s own blood. The process starts from drawing blood from the patient’s forearm, then transfer it to a centrifuge that spins very quickly. The rapid rotation of the centrifuge makes the different components of the blood separate from each other. When the spinning stops, the red blood cells and white blood cells are divided from the concentrated platelets and plasma. The platelets are the cell group that is responsible for clotting and the promotion of healing in the process of activating the growth factors that stimulates the body’s natural healing process.
The platelets consist of alpha granules that contain cytokines, growth factors and other essential proteins for the repair of connective tissues. These components aid in the bio regulatory activities inside the injured area which influence the repair of bones, cartilage and tendons, wounds, and the recuperation of blood loss. PRP also appears to have antibacterial and anti-fungal effects. These platelets are injected directly to the injured area and often times; these are areas that are hard to reach by the blood naturally.
Stanford University in Palo Alto, California and other researchers led by Dr. Allan Mishra have offered a commonly acknowledged medical hypothesis about PRP’s healing procedure on muscles, ligament and tendon regeneration. The team hypothesize PRP is administered to the tissue, though in its inactive form, the collagen in the connective tissue activates the platelet’s mechanism that releases growth factors and cytokines.
The chemical reactions stimulate the chromosomes to supplement the healing process and signal the local stem cell groups. The stem cells travel from your blood and bone marrow towards the injured site. During the time, cytokines and growth factors reduce inflammation at the site. They lessen the effects of bad proteins that are causing degeneration of joint cartilage in cases of osteoarthritis. Without this therapy, a typical osteoarthritic knee would need to be replaced within just 5 years from the onset of symptoms. The sought result of PRP treatment is the repair and regeneration of ligaments, muscle and cartilage thus permitting it to hold up more stress and weight without feeling any pain.